Benzodiazepine therapy can give rise to physiologic and psychologic dependence based on the drug's dosage, duration of therapy and potency. 1 Thus, dependence will develop sooner (such as in one to two months) in a patient who is taking a high dosage of a high-potency agent such as alprazolam than in a patient who is receiving a relatively low dosage of a long-acting, low-potency agent such as chlordiazepoxide. As a result of physiologic dependence, withdrawal symptoms emerge with rapid dose reduction or abrupt discontinuation of the drug.
In October 2008, the European Medicines Agency recommended the suspension of Acomplia after the Committee for Medicinal Products for Human Use (CHMP) had determined that the risks of Acomplia outweighed its benefits due to the risk of serious psychiatric problems, including suicide.  In November 2008 an advisory committee in Brazil recommended suspension as well, and that month Sanofi-Aventis suspended sale of the drug worldwide.  The EMA approval was withdrawn in January 2009.   In 2009 India prohibited the manufacture and sale of the drug. 
One of the most prevalent outcomes of abortion is shame and guilt that the mother suffers, sometimes for years. This is the most common postabortion syndrome symptom. A study in 2004 showed that just over 50% of American women who have had an abortion felt it was wrong to do so (Coleman, 4). This indicates that they probably did not want to have an abortion in the first place. Because they believe they are doing something wrong, they will have difficulty talking about it. Many women hide this secret. This self-protective measure is self-defeating, women need support and help if they are going to heal from the devastating effects of an abortion, yet many of them are too ashamed to talk about it.